Molecular Biology of RGS Proteins, a volume of Progress in Molecular Biology and Translational Science, will include historical discussion of RGS proteins, the role of RGS proteins in addiction, depression and Parkinson's disease and the biology and functional regulation of RGS9 isoforms. This publication further discusses RGS proteins in cellular signaling, protein control in lymphocyte function, and alternative splicing of RGS transcripts and nuclear RGS proteins, offering the latest in research of RGS proteins.
RGS Protein Physiology and Pathophysiology describes the current, state-of-the-art research occurring in the laboratories of leaders in the RGS protein field that utilize genetic mouse models to interrogate the function of RGS proteins in vivo. Each chapter describes the elucidated role of a specific RGS protein or family of RGS proteins in normal physiology and/or disease with particular emphasis on how these discoveries inform healthcare and drug discovery. The work is a timely reference as drugs targeting G protein coupled receptors represent 40% of currently marketed therapeutics. Brings together information on the current state of the RGS protein field Contains comprehensive descriptions of the known pathophysiological and physiological functions of RGS proteins, the first such undertaking Gives particular emphasis to the ways these discoveries inform healthcare and drug discovery
The Purpose Of This Book Is To Provide An Introductory Text For Understanding The Fundamental Principles Of Computer Graphics. Some Salient Features Are Chapters On Data Structures Along With Examples For Manipulating Pictures/Graphical Objects; Interactive Graphics Covering Input/Output Devices And Systems That Facilitate The Man-Machine Graphic Communication With Emphasis On Device-Independent Graphic Programming; 2-D And 3-D Graphics; Applications Of Graphics To Real-Life Problems, Such As Business Graphics, Graph Plotting, Line Drawing, Image Animation, 3-D Solid-Modeling, Fractals And Multi-Media. This Edition Includes Chapters On Multi-Media And Virtual Reality.
The need for greater bandwidth has driven laser manufacturers towards the use of distributed feedback semiconductor (DFB) lasers with a well-defined single mode. These semiconductor diode-based devices are now essential components in a broad range of advanced optical systems. This text covers the materials, operation and design strategies of DFB lasers. It provides detailed accounts of large-signal time-domain numerical modelling techniques, which can be extended to optical systems and components other than DFB lasers. Numerical MATLAB programs are outlined in the text.
Hardbound; 8 1/2 x 11 inches; 416 pages; indexed; w/deluxe plastic dust jacket; 31 full-color photos; 374 historic black & white views. Produced with the classic Sundance flair! Loaded with detailed right-of-way maps, including Ridgway to Vance Junction--recently made available and not presented in the previous volumes. Tucked in the dust jacket is an 18" x 24" system map that includes large-scale inset maps of various station grounds and the Ophir Loop, etc. This volume covers the full 162 miles of this fabled narrow-gauge steam railroad.
Regulators of G Protein Signaling, Part B continues the in-depth treatment of the topic and covers the RSG protein superfamily including RZ, R4, R7, R12, RhoGEF, and GRK, as well as other heterotrimeric G-protein signaling regulators. Table of Contents RZ Subfamily R4 Subfamily R7 Subfamily R12 Subfamily RhoGEF Subfamily GRK Subfamily Other RGS proteins Activators Inhibitors Other Modulators